Abstract

The advancement of photocatalytic materials is critical for addressing environmental challenges such as water remediation, where efficient, robust, and reusable systems are in high demand. In this search, the development of hierarchically organized photocatalytic configurations with spatial control over active sites can significantly enhance performance. With this in mind, we present here a novel biomimetic approach for the patterned growth of TiO2-ZnO photocatalytic heterostructures using solid-binding peptides (SBPs) as molecular linkers. Specifically, using bi-functional SBPs with selective affinity for both oxides, we achieve site-specific, molecularly guided deposition of TiO2 nanoparticles onto pre-patterned ZnO-coated substrates. Leveraging the specific recognition capabilities and strong binding affinities of the engineered SBPs, the proposed biomimetic methodology allows for the fabrication of well-organized hybrid nanostructures under sustainable conditions. Photocatalytic degradation assays employing methyl orange as a model contaminant indicate that the patterned architecture enhances both the accessibility of the active photocatalytic sites and the recoverability of the material. This reusability is a critical parameter for the practical deployment of photocatalytic systems in water purification technologies. The obtained results underscore the potential of SBP-mediated molecular recognition as a versatile tool for green nanofabrication of functional materials with advanced architectural and catalytic properties.